British Air Force Typhoon fighter aircraft have operated alongside French warplanes in a joint strike targeting an hidden munitions depot in Syria used by the IS group, per a report from the UK's MoD.
The site, located using surveillance, was believed to be housing weapons and explosive materials, the statement said, and was positioned in hills just above the ancient city of Palmyra in the heart of Syria.
"Our fighter planes employed laser-guided Paveway IV weapons to target a series of approach shafts providing entry to the facility... early reports are that the strike was effective," the MoD said.
There was no indication of any harm to civilians in the attack on Saturday evening and every plane involved returned to base without incident, the MoD added.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - referred to as the so-called Islamic State - established jihadist rule over parts of both Syria and Iraq prior to its 2019 collapse.
"This operation demonstrates British leadership, and commitment to stand shoulder to shoulder with our partners, to eradicate any revival of the terrorist group and their harmful and extremist ideologies in the Middle East," UK Defence Secretary the Defence Secretary said.
UK warplanes have performed overwatch operations over Syria to "deter any attempted resurgence" of Islamic State following its defeat at the battle of Baghuz in 2019, the MoD reported.
"I want to thank the personnel of British forces involved in this mission for their expertise and their valour," the Defence Secretary said. "Including them were numerous British troops deployed over the festive period. This action, to remove militants who endanger our security, shows how UK forces are always on standby, throughout the year, ensuring Britain's security at home and strong abroad."
During December, the United States armed forces conducted what it described as a "massive strike" against Daesh sites in Syria, subsequent to an assault resulted in the deaths of two US servicemembers and a civilian linguist in the Palmyra area.
The UN says IS still boasts an estimated 5,000 to 7,000 combatants in both countries.